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Effect of Vitamin E on Blood Pressure of Hemodialysis Patients

The assessment of oral vitamin E on blood pressure compared to the placebo in patients with chronic renal failure receiving hemodialysis 2024- (A double blind randomized clinical trial)

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20090701002113N3
Enrollment
30
Registered
2024-06-30
Start date
2024-07-10
Completion date
Unknown
Last updated
2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Kidney Disease. Chronic kidney disease, stage 5

Interventions

Intervention 1: Intervention group: Receiving oral capsule of Vitamin E. Intervention 2: Control group: Receiving oral capsule of placebo.

Sponsors

Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Hemodialysis Patients 18-70 years old Shiraz University of Medical Sciences HD center Maintenance HD at least for 3 months

Exclusion criteria

Exclusion criteria: Smoking and alcohol consumer Anti-oxidant supplements use Liver or Heart Failure Diabetes mellitus Obstructive uropathy Endocrine cancers Hemoglobine <9 mg/dL Coronary vessels disease

Design outcomes

Primary

MeasureTime frame
Blood Pressure (systolic and diastolic). Timepoint: Before the intervention, the beginning of the intervention (the first day), the end of each week after the intervention and the end of the intervention (the end of the eighth week). Method of measurement: Measure blood pressure using sphygmomonometer.

Secondary

MeasureTime frame
Effect of vitamin E on serum creatinine. Timepoint: Before and after 8 weeks of intervention. Method of measurement: Jaffe method - Autoanalyzer.;Effect of vitamin E on hemoglobine. Timepoint: Before and after 8 weeks of intervention. Method of measurement: cyanmethemoglobin method (CM)- Spectrophotometric method.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactJamshid Roozbeh

Shiraz University of Medical Sciences

roozbehj@hotmail.com+98 71 3628 1528

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026