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Determination of the Preventive Effect of Desmopressin Acetate on the incidence of bleeding complications following kidney biopsy in patients with renal disease

Determination of the Preventive Effect of Desmopressin Acetate on the incidence of bleeding complications following kidney biopsy in patients with renal disease

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20090701002112N3
Enrollment
146
Registered
2020-10-04
Start date
2017-11-22
Completion date
Unknown
Last updated
2020-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic kidney patients. Chronic kidney disease, unspecified

Interventions

Intervention 1: Based on the block of redundancy and the patient in the intervention group, 1 hour before biopsy, desmopressin acetate is received in the nose and 1 kg / kg. After 1 hour, the ultrasou

Sponsors

Ahvaz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: People 18 years and older 15=GFR=90 cc/min/1.73 m2 according MDRD formula

Exclusion criteria

Exclusion criteria: Disrupted coagulation profile (including disruption in any of the PT tests, INR, PTT, and platelet counts are less than 50000 Systrelic Blood Pressure Time Biopsy less than160mmhg Diastolic BP Time to do biopsy less than100mmhg Single kidney Kidney cancer Renal hydronephrosis Renal Pyrenophore Small size Significant kidneys in ultrasound Severe obesity Hemoglobin less than 11 Sodium concentration in serum less than 120 Primary phenotypes Renal transplantation Multiple cysts in both kidneys

Design outcomes

Primary

MeasureTime frame
Hematoma. Timepoint: Immediately after receiving a kidney biopsy specimen and 24 hours later, and in the event of a hematoma, 48-72 hours later. Method of measurement: Ultrasonography.

Secondary

MeasureTime frame
Hematuria. Timepoint: After biopsy. Method of measurement: View at any time urinating.;Vital signs l (blood pressure and heart rate). Timepoint: Every 15 minutes for 2 hours, then every 1 hour for 4 hours, then every 2 hours for 6 hours, and then every 4 hours. Method of measurement: Device.;Flank pain. Timepoint: Follow up on every visit. Method of measurement: Physical exam.;Biochemical Factors (Sodium, Hemoglobin, Hematocrit). Timepoint: 24 hours after biopsy. Method of measurement: Blood test.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Ali Ghorbani

Ahvaz University of Medical Sciences

ghorbani-a@ajums.ac.ir+98 61 3373 8383

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026