Candidate Patients Receiving Skin Transplant.
Conditions
Interventions
Intervention 1: First Intervention: patients receiving 0.25% timolol gel The first dose will be applied immediately after the operation. The gel will be used twice daily fo
Sponsors
Sari University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Age =18 years of age Undergoing a procedure which results in the need of a STSG Willing to provide written informed consent
Exclusion criteria
Exclusion criteria: Pregnant women and breastfeeding Use of systemic beta blockers drugs or topical except timolol Hypersensitivity to timolol or other beta blockers Severe, uncontrolled systemic comorbidities, such as diabetes, asthma, Chronic obstructive pulmonary disease Use of systemic drugs that can impede wound healing, such retinoids or immune-suppressive drugs Severe coagulation disorders including a lack of coagulation factors and immunologic thrombocytopenic purpura
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Duration of wound epithelization in donor site of the transplant. Timepoint: The evaluation of wound on days 0 and 3 and 7 and 14 after surgery. Method of measurement: Clinical observation regarding the wound epithelization. | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain severity. Timepoint: The evaluation times include days 0 (time of skin removal),3 ,7, 14 and 3 months after surgery. Method of measurement: Visual Analogue Scale.;?Evaluation of the scar status. Timepoint: Three months after surgery. Method of measurement: Vancouver Scar Scale (VSS) and The Patient and Observer Scar Assessment Scale (POSAS). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactEbrahim Salehifar
Sari University of Medical Sciences
Outcome results
None listed