Effect of Oxycodone plus Lorazepam in pain induced by Bone marrow Aspiration and Biopsy

Evaluation of the effect of Oxycodone plus Lidocaine plus Lorazepam in combination versus Lidocaine alone in pain induced by Bone marrow Aspiration and Biopsy (BMAB) in Mazandaran Cancer Center

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20090613002027N13

Enrollment

Registered

2018-08-04

Start date

2018-08-23

Completion date

Unknown

Last updated

2018-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

bone marrow and aspiration biopsy related pain. Unspecified complication of procedure

Interventions

Intervention 1: 5ml lidocaine hydrochloride 1% during bone marrow aspiration and biopsy. Intervention 2: 2mg lorazepam tablet 30 minutes before bone marrow aspiration and biopsy. Intervention 3: 10mg

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients older than 18 years (inpatient or outpatient) Patients who are candidate for Bone Marrow Aspiration and Biopsy (BMAB) in Mazandaran Cancer Center

Exclusion criteria

Exclusion criteria: Mental disorder Language problems Unwillingness to participate in the study

Design outcomes

Primary

Measure	Time frame
Pain Score following bone marrow aspiration/biopsy. Timepoint: 10 minutes following Bone marrow Aspiration and Biopsy. Method of measurement: Visual Analogue Scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactEbrahim Salehifar

Faculty of Pharmacy, Mazandaran University of Medical Sciences

salehifare@yahoo.com+98 11 3354 3241

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026