Investigating the influence of temperature change of analgesia liquid on analgesia success

The influence of Lidocaine temperature change on injection pain and analgesia success in maxillary central incisors

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20090609002016N10

Enrollment

100

Registered

2018-10-13

Start date

2018-11-08

Completion date

Unknown

Last updated

2018-11-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthesia injection pain.

Interventions

Intervention 1: Intervention group1: Injection single dose of Lidocaine 2% with Epinephrine 1:80000 (Iran, Tehran, Darupakhsh) at 37 C temperature to 50 volunteer. Intervention 2: Intervention group 2

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age more than 18 years No consumption of analgesic and antidepressant medications during recent 48 hours No contraindications or sensitivity for injecting lidocaine with epinephrine Having no systemic disease

Exclusion criteria

Exclusion criteria: No response to the cold test Having sensitivity to percussion Having sensitivity to palpation Previous history of root canal therapy Internal or external resorption

Design outcomes

Primary

Measure	Time frame
Pain during injection. Timepoint: At the time of local anesthetic injection. Method of measurement: Using visual analoug scale (VAS).;Success rate of anesthetic depth. Timepoint: After injection of local anesthesia. Method of measurement: Pulp tester.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMasoud Parirokh

Kerman University of Medical Sciences

m_parirokh@kmu.ac.ir+98 342118074

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026