Assessment of pregnancy rate by laparoscopic ovarian cautery in patients with poly cystic ovary syndrome and Previous failed IVF procedures

Assessment of infertility treatment success by laparoscopic ovarian cautery in patients with poly cystic ovary syndrome and Previous failed IVF procedures referred to infertility clinic of Arash women hospital: a clinical trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20090526001952N14

Enrollment

Registered

2021-02-17

Start date

2016-12-04

Completion date

Unknown

Last updated

2023-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

infertility. Female infertility associated with anovulation

Interventions

Intervention 1: Intervention group: Laparoscopic ovarian drilling is performed using 40-watt bipolar current at 4-6 points of the ovaries for patients and a month later undergo in vitro fertilization

Eligibility

Sex/Gender

Female

Age

18 Years to 39 Years

Inclusion criteria

Inclusion criteria: Women with poly cystic ovary syndrome who have two of the three diagnostic criteria Rotterdam at least Age between 18- 35 year- old Body mass index less than 30 Normal semen analysis in their spouse Previous failed IVF procedures at least for 2 times No laparoscopic contraindications

Exclusion criteria

Exclusion criteria: Aged more than 39 year Previous ovarian surgery Co-existing endocrine diseases including diabetes mellitus, estrogen-dependent tumors, thyroid disease, Cushing’s syndrome, or congenital adrenal hyperplasia

Design outcomes

Primary

Measure	Time frame
Chemical pregnancy rate. Timepoint: Beta-hCG test 14 days after embryo transfer. Method of measurement: Laboratory kits for Beta-hCG assay.;Clinical pregnancy rate. Timepoint: 6 to 7 weeks after embryo transfer. Method of measurement: Observing the gestational sac along with fetal heart activity in vaginal ultrasound.	—

Secondary

Measure	Time frame
Oocyte quality. Timepoint: Ovum pick-up day. Method of measurement: The number of Metaphase II oocytes obtained on the day of ovulation, which is reported by the embryologist.;Abortion rate. Timepoint: before 20th week of pregnancy. Method of measurement: sonography.;Embryo quality. Timepoint: before transfer. Method of measurement: It is determined by the embryologist based on the number of blastomeres and the percentage of fragmentation, multinucleation and symmetry on the third day after oocyte retrieval.;Live birth rate. Timepoint: The delivery of a fetus who shows evidence of life after that is entirely outside of the mother. Method of measurement: Through hospital reports and telephone follow-up of patients.;The pregnancy complications. Timepoint: during 9 months of pregnancy. Method of measurement: Complications such as premature delivery or premature rupture of the amniotic sac before 37 weeks of pregnancy and diagnosis of blood pressure above 140/90 (hypertension) along with edema and excretion of protein in the urine (Preeclampsia) as well as diagnosis of gestational diabetes (fasting plasma glucose equal to or greater than 92 mg/dL) with glucose 1 hour after consuming 75 grams of glucose equal to or more than 180 mg/dL) is recorded through checking the hospital report and telephone follow-up.;Ovarian hyperstimulation syndrome rate. Timepoint: 3 and 10 days after ovarian puncture. Method of measurement: Examination of symptoms, signs of ovarian hyperstimulation (mild to moderate pain in the abdomen, bloating or increased waist size, nausea and vomiting, diarrhea, tenderness in the ovaries) and vaginal ultrasound.	—

Measure

Time frame

Oocyte quality. Timepoint: Ovum pick-up day. Method of measurement: The number of Metaphase II oocytes obtained on the day of ovulation, which is reported by the embryologist.;Abortion rate. Timepoint: before 20th week of pregnancy. Method of measurement: sonography.;Embryo quality. Timepoint: before transfer. Method of measurement: It is determined by the embryologist based on the number of blastomeres and the percentage of fragmentation, multinucleation and symmetry on the third day after oocyte retrieval.;Live birth rate. Timepoint: The delivery of a fetus who shows evidence of life after that is entirely outside of the mother. Method of measurement: Through hospital reports and telephone follow-up of patients.;The pregnancy complications. Timepoint: during 9 months of pregnancy. Method of measurement: Complications such as premature delivery or premature rupture of the amniotic sac before 37 weeks of pregnancy and diagnosis of blood pressure above 140/90 (hypertension) along with edema and excretion of protein in the urine (Preeclampsia) as well as diagnosis of gestational diabetes (fasting plasma glucose equal to or greater than 92 mg/dL) with glucose 1 hour after consuming 75 grams of glucose equal to or more than 180 mg/dL) is recorded through checking the hospital report and telephone follow-up.;Ovarian hyperstimulation syndrome rate. Timepoint: 3 and 10 days after ovarian puncture. Method of measurement: Examination of symptoms, signs of ovarian hyperstimulation (mild to moderate pain in the abdomen, bloating or increased waist size, nausea and vomiting, diarrhea, tenderness in the ovaries) and vaginal ultrasound.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSakineh Normohamadi

Tehran University of Medical Sciences

sakineh.nour@gmail.com+98 21 7771 9922

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026