Polycystic Ovary Syndrome. Polycystic Ovarian Syndrome
Conditions
Interventions
Intervention 1: Intervention Group: The First Group (50 Patients) Treated With Metformin 500 Mg Three Times Daily (First Week 500 Mg Daily And Then Second Week 500 Mg Twice Daily And Third Week 500 Mg
Sponsors
Yazd University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: Ages 18 to 40 Observe 12 Follicles Or More In Size Of 2-9 Mm In The Ovary By Ultrasound Oligomenorrhea or Amenorrhea In The Last 6 Months Testosterone Levels Above 0.7 ng/dl Serum Insulin Levels Above 16 U/ml
Exclusion criteria
Exclusion criteria: Pregnancy And Lactation During The Last 90 Days And Discontinuation Of Medication During Treatment Liver And Kidney Failure During The Last 90 Days And Discontinuation Of Medication During Treatment Thyroid Dysfunction During The Last 90 Days And Discontinuation Of Medication During Treatment Hyper Prolactinemia During The last 90 Days And Discontinuation Of Medication During Treatment Adrenal Dysfunction During The Last 90 Days And Discontinuation Of Medication During Treatment Congenital Adrenal Hyper Plasia During The Last 90 Days And Discontinuation Of Medication During Treatment Cushing's Syndrome During The Last 90 Days And Discontinuation Of Medication During Treatment Use Of Contraceptives During The Last 90 Days And Discontinuation Of Medication During Treatment Taking Estrogen And Progesterone In The Last 90 Days And Discontinuing Medication During Treatment Ovulation Induce Medication For The Last 90 Days And Discontinue Medication During Treatment Use Of Anti-Androgen Drugs During The Last 90 Days And Discontinuation Of Medication During Treatment Insulin Use During The Last 90 Days And Discontinuation Of Medication During Treatment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum Insulin Level. Timepoint: Before Intervention And After Intervention( After Three Month). Method of measurement: µU/ml.;Low Density Lipoprotein. Timepoint: Before Intervention And After Intervention( After Three Month). Method of measurement: Mili Gram Per Deciliter.;High Density Lipoprotein. Timepoint: Before Lntervention And After Intervention( After Three Month). Method of measurement: Mili Gram Per Deciliter.;Triglyceride. Timepoint: Before Intervention And After Intervention( After Three Month). Method of measurement: Mililgram Per Deciliter.;Fast Blood Suger. Timepoint: Before Intervention And After Intervention( After Three Month). Method of measurement: Milligram Per Deciliter.;17hydroxyprogestrone. Timepoint: Before Intervention And After Intervention( after three month). Method of measurement: Miligram Per Liter.;Total Testosterone. Timepoint: Before Intervention And After Intervention( After Three Month). Method of measurement: Microgram Per Liter.;LH/FSH Ratio. Timepoint: Before Intervention And After Intervention( After Three Month). Method of measurement: IU Per Liter.;Cholesterol. Timepoint: Before Intervention And After Intervention( After Three Month). Method of measurement: Milligram Per Deciliter. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFaculty of Pharmacy- Shahid Sadoughi University of Medical Sciences
Yazd University of Medical Sciences
Outcome results
None listed