Acute neonatal seizure. Epilepsy and recurrent seizures
Conditions
Interventions
Intervention 1: Intervention group: Levetiracetam made by Estragen Company, Switzerland with initial loading dose of 30 mg/kg with slow intravenous infusion is injected for 15 minutes and maintenance
Sponsors
Sari University of Medical Sciences
Eligibility
Sex/Gender
All
Age
1 Days to 28 Days
Inclusion criteria
Inclusion criteria: Term neonates Age = 28 days Clinical seizures requiring treatment based on the diagnosis of a neonatalologist Seizure diagnosis based on pediatric neurologist diagnosis and EEG interpretation Written informed consent of parents
Exclusion criteria
Exclusion criteria: Renal failure Seizures caused by electrolyte disorders such as hypocalcemia and hypoglycemia Patients whose seizures respond to vitamin B6 administration Sensitivity to Levetiracetam or phenobarbital Structure Anomaly Asphyxia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Seizure. Timepoint: 30 min, 24 hour up to 1 week, 1st month, 2nd month, 3rd month. Method of measurement: Clinical examination and observation of paroxysmal movements of the neonate. | — |
Secondary
| Measure | Time frame |
|---|---|
| Sizure recurrence. Timepoint: 30 min, 24 hour up to 1 week, 1st month, 2nd month, 3rd montt. Method of measurement: Clinical examination and observation. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Ali Abbaskhanian
Sari University of Medical Sciences
Outcome results
None listed