Study lipase inhibitor and Alpha-glucosidase inhibitor in control of weight in obese patient

Study on the effects of co-administration of lipase inhibitor and Alpha-glucosidase inhibitor in control of weight in obese patient

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20090317001774N9

Enrollment

Registered

2018-09-19

Start date

2018-03-21

Completion date

Unknown

Last updated

2018-10-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: . Condition 2: obesity. Overweight and obesity

Interventions

Intervention 1: First Intervention group: The recipient of Orlistat (three daily food supplements, 180 mg) for 6 months. Intervention 2: Second Intervention group: The recipient of Orlistat and Acarbo

Eligibility

Sex/Gender

All

Age

20 Years to 50 Years

Inclusion criteria

Inclusion criteria: Age 20 to 50 years Lack of underlying illness BMI>30

Exclusion criteria

Exclusion criteria: Fasting Blood Glucose Over 250 Hemoglobin A1C higher than 9% Insulin therapy Chronic inflammatory disease Chronic complications of diabetes Pregnancy Lactation Liver Diseases Kidney Diseases Neurological diseases

Design outcomes

Primary

Measure	Time frame
Blood glucose after 8 hours of fasting. Timepoint: Before intervention and 6 months after intervention. Method of measurement: Spectrophotometer.;Measuring low density lipoprotein in serum. Timepoint: Before intervention and 6 months after intervention. Method of measurement: Using an auto-analyzer method.;Measuring high density lipoprotein in serum. Timepoint: Before intervention and 6 months after intervention. Method of measurement: Using an auto-analyzer method.;Measuring blood cholesterol. Timepoint: Before intervention and 6 months after intervention. Method of measurement: Using an auto-analyzer method.;Measuring blood triglycerides. Timepoint: Before intervention and 6 months after intervention. Method of measurement: Using an auto-analyzer method.;Insulin measurement. Timepoint: Before intervention and 6 months after intervention. Method of measurement: Using ELISA test.	—

Measure

Time frame

Blood glucose after 8 hours of fasting. Timepoint: Before intervention and 6 months after intervention. Method of measurement: Spectrophotometer.;Measuring low density lipoprotein in serum. Timepoint: Before intervention and 6 months after intervention. Method of measurement: Using an auto-analyzer method.;Measuring high density lipoprotein in serum. Timepoint: Before intervention and 6 months after intervention. Method of measurement: Using an auto-analyzer method.;Measuring blood cholesterol. Timepoint: Before intervention and 6 months after intervention. Method of measurement: Using an auto-analyzer method.;Measuring blood triglycerides. Timepoint: Before intervention and 6 months after intervention. Method of measurement: Using an auto-analyzer method.;Insulin measurement. Timepoint: Before intervention and 6 months after intervention. Method of measurement: Using ELISA test.

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Secondary

Measure	Time frame
Weight. Timepoint: Before intervention and 6 months after intervention. Method of measurement: Scales.;Height. Timepoint: Before intervention and 6 months after intervention. Method of measurement: meter.;Waist. Timepoint: Before intervention and 6 months after intervention. Method of measurement: meter.;Hip circumference. Timepoint: Before intervention and 6 months after intervention. Method of measurement: meter.;BMI. Timepoint: Before intervention and 6 months after intervention. Method of measurement: The squared height is divided by weight.;WHR. Timepoint: Before intervention and 6 months after intervention. Method of measurement: Computing.	—

Measure

Time frame

Weight. Timepoint: Before intervention and 6 months after intervention. Method of measurement: Scales.;Height. Timepoint: Before intervention and 6 months after intervention. Method of measurement: meter.;Waist. Timepoint: Before intervention and 6 months after intervention. Method of measurement: meter.;Hip circumference. Timepoint: Before intervention and 6 months after intervention. Method of measurement: meter.;BMI. Timepoint: Before intervention and 6 months after intervention. Method of measurement: The squared height is divided by weight.;WHR. Timepoint: Before intervention and 6 months after intervention. Method of measurement: Computing.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Ehsan Aali

Qazvin University of Medical Sciences

e.aali@qums.ac.ir+98 28333360015

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026