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The effect of consuming black seed capsules on complications caused by premenstrual syndrome

Comparison of the effect of Nigella sativa capsule and placebo on the severity of premenstrual syndrome symptoms in affected women: a randomized clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20090304001742N12
Enrollment
28
Registered
2025-12-22
Start date
2026-01-10
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

premenstrual syndrome. Premenstrual tension syndrome

Interventions

Intervention 1: Intervention group: The intervention included taking 1 capsule of 1000 mg of black seed daily for 7 days. Intervention 2: Control group: Received placebo, consisting of a capsule conta

Sponsors

Larestan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Willingness to participate in the research, completing a written informed consent form Having a regular menstrual cycle of 21 to 35 days, diagnosed with premenstrual syndrome Age between 18 and 35 years Diagnosis of premenstrual syndrome

Exclusion criteria

Exclusion criteria: Presence of specific underlying diseases Presence of diseases related to the reproductive system Use of medications affecting premenstrual syndrome Use of antidepressant medications Use of hormonal medications or oral contraceptive pills Experience of major stressful events such as the death of a first-degree relative within the past year Cigarette smoking

Design outcomes

Primary

MeasureTime frame
Premenstrual Symptoms Screening Questionnaire Score. Timepoint: Before the intervention and immediately after the intervention. Method of measurement: Premenstrual Symptom Index Scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad rafi Bazrafshan

Larestan University of Medical Sciences

m.bazrafshan@larums.ac.ir+98 71 5225 5512

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 7, 2026