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The effect of designing and implementation of "daily interruption of sedative drugs" guidelines on the duration of mechanical ventilation in Adult Central and General intensive care units of Namazi hospital ,Shiraz,Iran

The effect of designing and implementation of “daily sedation interruption “ protocol on the duration of mechanical ventilation in Adult Central and General intensive care units of Namazi hospital ,Shiraz,Iran

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20090119001566N5
Enrollment
80
Registered
2023-06-21
Start date
2023-08-01
Completion date
Unknown
Last updated
2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

critical care.

Interventions

Intervention 1: Intervention group (first group): After reviewing the guidelines and protocols of the world regarding sedation drugs interruptions in patients undergoing mechanical ventilation, A team

Sponsors

Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients older than 18 years Intubated patients under mechanical ventilation

Exclusion criteria

Exclusion criteria: Active seizure Patients who have received Neuromuscular blocking agents medication Moderate to severe shock The signs of increased intracranial pressure A patient who will undergo surgery in the next 24 hours Predicting imminent death in less than 48 hours Induced hypothermia Active cardiac ischemia in the last 24 hours patients who refuced to participate in the study

Design outcomes

Primary

MeasureTime frame
Duration of mechanical ventilation. Timepoint: From the time the patient enters the ICU until discharge from this ward. Method of measurement: Number of days the patient is under mechanical ventilation based on patients recorded information.

Secondary

MeasureTime frame
Mortality rate. Timepoint: Duration of hospitalization. Method of measurement: Mortality counting based on patients recorded information.;ICU length of stay. Timepoint: From the time of the patient's arrival until the discharge of ICU. Method of measurement: According to the number of days the patient was hospitalized in the ICU.;Extubation time. Timepoint: ICU length of stay. Method of measurement: Using patient records.;Diagnosis. Timepoint: Duration of hospitalization. Method of measurement: Using patient records.;The amount of sedative medication. Timepoint: ICU length of stay. Method of measurement: Using patient records.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahtab Setoode

Shiraz University of Medical Sciences

mahtab.setoodeh@yahoo.com+98 71 3647 4270

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026