Schizophrenia. Schizophrenia
Conditions
Interventions
Intervention 1: ?Control group: Patients treated with risperidone (Poursina co.) at a dose of 4-6 mg along with placebo. The chemical formula of risperidone is C23H27FN4O2, which is administered orall
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Diagnosis of schizophrenia based on DSM-5 Age between 18-60 At least 2 years have been passed since the diagnosis Treated with risperidone for at least 2 months (4-6mg)
Exclusion criteria
Exclusion criteria: Head trauma History of shock therapy during the last three months Neurosurgery Diagnosis of acute or chronic systemic disease Alcohol or drug addiction in the last 6 months Suicidal ideation Pregnancy or lactation IQ less than 70 based on the diagnosis of a psychiatrist Depressive symptoms and use of antidepressants
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of schizophrenia. Timepoint: Baseline and weeks 4 and 8. In the present study, the severity of negative symptoms will be evaluated at day 0, 4 weeks after treatment, and 8 weeks after treatment. Method of measurement: By Positive and Negative Syndrome Scale (PANSS). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Shahin Akhondzadeh
Tehran University of Medical Sciences
Outcome results
None listed