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Sulforaphane for the treatment of ADHD

Sulforaphane as an adjuvant therapy in children with attention-deficit/hyperactivity disorder (ADHD): A randomized, double-blind, placebo-controlled clinical trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20090117001556N146
Enrollment
50
Registered
2022-09-13
Start date
2022-10-23
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ADHD. Attention-deficit hyperactivity disorder, combined type

Interventions

Intervention 1: Control group: According to the patient's condition, the dose of Ritalin is 0.1 to 3.5 mg per kilogram of body weight + placebo daily for 8 weeks. Intervention 2: Intervention group: A

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
6 Years to 11 Years

Inclusion criteria

Inclusion criteria: Age between 6-11 years Diagnosis of ADHD based on DSM5

Exclusion criteria

Exclusion criteria: Age range outside 6-11 years Diagnosis of a serious disease, or disease requiring surgery, or neurological diseases Diagnosis of a psychiatric disorder and taking neuropsychiatric drugs, except for ADD History of treatment with sulforaphane in the last three months History of treatment with neuroleptic medication in the last six months Weight less than 13.5 kg Mental retardation Seizure A systolic blood pressure greater than 125 or a resting heart rate less than 60 or greater than 115 History of allergy to sulforaphane or methylphenidate

Design outcomes

Primary

MeasureTime frame
Severity of ADHD. Timepoint: Weeks: 0 , 4 , 8. Method of measurement: By ADHD Rating Scale (by parents or teacher).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Shahin Akhondzadeh

Tehran University of Medical Sciences

s.akhond@sina.tums.ac.ir+98 21 5541 2222

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026