En Irritable bowel syndrome. Irritable bowel syndrome
Conditions
Interventions
Intervention 1: Intervention group: Capsule Vortioxetine 10mg/day as intervention group for 6 weeks. Intervention 2: Control group: receiving placebo for 6 weeks.
Treatment - Drugs
Placebo
Intervention group: Capsule Vortioxetine 10mg/day as intervention group for 6 weeks
Control group: receiving placebo for 6 weeks
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: age 18-65 years old IBS diagnosis through ROME IV criteria moderate to severe symptoms through severity of symptom
Exclusion criteria
Exclusion criteria: diagnosis of any organic disease related to symptoms any psychiatric disorder pregnancy taking any other psychotropic drugs during 4 weeks before entering to the trial breastfeeding
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of symptom. Timepoint: Baseline and weeks 2-4-6 after beginig of treatment. Method of measurement: IBS-SSS questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of life. Timepoint: Baseline and weeks 2-4-6 after beginig of treatment. Method of measurement: IBS QOL. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactShahin Akhondzadeh
Tehran University of Medical Sciences
Outcome results
None listed