autistic disorder. Autistic disorder
Conditions
Interventions
Intervention 1: Intervention group: Tablet Resveratrol( 500 mg per day) plus Risperidone ( 1 to 3.5 mg per day) for 12 weeks. Intervention 2: Control group: Tablet placebo plus Risperidone( 1 to 3.5 m
Treatment - Drugs
Placebo
Intervention group: Tablet Resveratrol( 500 mg per day) plus Risperidone ( 1 to 3.5 mg per day) for 12 weeks
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
3 Years to 12 Years
Inclusion criteria
Inclusion criteria: DSM-5 clinical diagnosis of autistic disorder children between the ages of 3 and 12 years presence of behavioral problems such as aggression, overactivity or repetitive behaviors (indication of treatment with risperidone)
Exclusion criteria
Exclusion criteria: Presence of any active medical problem other psychiatric diagnosis except for mild to moderate Intellectual disability receiving any antipsychotic medications during past monthprior to the trial severe hepatic disease history of allergy to risperidone and intolerance of it History of seizure requiring change of antiepileptic dose during the last month seizure during the last 6 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of autism. Timepoint: Baseline and weeks 4, 8 and 12. Method of measurement: By Aberrant Behavior Checklist-Community( ABC-C) and Childhood Autism Rating scale( CARS). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactShahin Akhondzadeh
Roozbeh Psychiatric Hospital, Tehran University of Medical Sciences
Outcome results
None listed