Leishmania. Cutaneous leishmaniasis
Conditions
Interventions
Intervention 1: Intervention group: Once injection per week. Intervention 2: Intervention group: Twice a week.
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
8 Years to 70 Years
Inclusion criteria
Inclusion criteria: 80-70 year old patients with clinically suspected CL lesion(s) with Parasitological proven (smear and/or culture) CL patients caused by L. tropica were recruited into the study if they met other eligibility criteria. Polymers chain reaction (PCR) was performed on every sample to assure that the lesion was caused by L. tropica. Other inclusion criteria were age 8-70 years, willingness to participate in the trial, and sign an informed consent and an oral assent from the children.
Exclusion criteria
Exclusion criteria: Patients with lesion(s) duration more than 6 months, more than 4 lesions, ulcer size more than 3 cm, lesions on the face or close to a vital organ, pregnant and nursing patients, those with a history of previous systemic or IL treatment with MA or those with an acute or chronic disease that could affect the course of CL or treatment with IL-MA injections were excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome of the study was complete cure defined as complete re-epithelialization of the lesion with no induration. Timepoint: Before the intervention and every week. Method of measurement: Measurement of the lesion. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAli Khamesipour
Tehran University of Medical Sciences
Outcome results
None listed