allergic rhinitis. Allergic rhinitis due to pollen
Conditions
Interventions
Intervention 1: Intervention group: Zofi Bell syrup is a combination of Nepeta bracteata extract, Adiantum capillus-venerisand Althaea officinalis, produced by Sanabel Daru Company, licensed by the F
Sponsors
Shahed University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Allergic rhinitis, both seasonal and permanent (intermittent and continuous) Having criteria for allergic rhinitis based on the ARIA form
Exclusion criteria
Exclusion criteria: The presence of chronic diseases such as asthma, diabetes, cancer, as well as trauma and recent nose surgery, and women who are pregnant and breastfeeding. Taking any chemical and herbal medicine known to be effective on allergic rhinitis lack of literacy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gene expression levels of IL-5, IL-17A, interferon gamma, IL-4, IL-10, IL-13. Timepoint: The medicine will be taken for 4 weeks. Blood sampling will be at the beginning of the study and after the end of the medication in the fourth week. Method of measurement: with laboratory tests, respectively 1. Isolation of peripheral blood mononuclear cells (PBMCs); 2. Total RNA extraction; 3. cDNA synthesis; 4. Quantitative Real-Time PCR (qRT-PCR)Open in Google Translate•F. | — |
Secondary
| Measure | Time frame |
|---|---|
| Drug side effects. Timepoint: Second and fourth week. Method of measurement: Medication side effects questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMohsen Naseri
Shahed University
Outcome results
None listed