Patent ductus arteriosus. Patent ductus arteriosus
Conditions
Interventions
Intervention 1: Intervention group: Premature newborn with a gestational age of less than 30 weeks will receive intravenous acetaminophen at 10 mg/kg every 6 hours for up to 3 days. Intervention 2: Co
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
1 Days to 30 Days
Inclusion criteria
Inclusion criteria: Consent to participate in the study Premature babies with a gestational age of less than 30 weeks Premature infants without evidence of patent ductus arteriosus
Exclusion criteria
Exclusion criteria: CHF Liver or kidney disease or cholestasis congenital heart disease PPHN Genetic disorders and congenital malformations Apgar score 5 minutes less than 5 PH <7.2 Septicemia Difference in pre-duct and post-duct oxygen saturation is more than 3%
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluating the effect of prophylactic acetaminophen intervention on the clinical manifestations of premature infants with a gestational age of less than 30 weeks. Timepoint: every 6 hours for three days. Method of measurement: The first dose will be prescribed after 12 hours of birth to provide enough time to examine the baby for underlying cardiac pathology, then every 6 hours for three days. | — |
Secondary
| Measure | Time frame |
|---|---|
| Sepsis. Timepoint: Every 6 hours for three days. Method of measurement: through laboratory tests.;Intraventricular hemorrhage. Timepoint: Every 6 hours for three days. Method of measurement: By sonography of the skull through the anterior fontanel.;Retinopathy of prematurity. Timepoint: Every 6 hours for three days. Method of measurement: Use of Ret Cam.;Bronchopulmonary dysplasia. Timepoint: Every 6 hours for three days. Method of measurement: Newborn age and oxygen need. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSamira Alinezhad
Mashhad University of Medical Sciences
Outcome results
None listed