Effects of probiotics in bilirubin increase

Comparison of the effectiveness of probiotics against bilirubin increase in neonates below 2500 gram.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20081021001378N13

Enrollment

100

Registered

2021-12-29

Start date

2021-01-06

Completion date

Unknown

Last updated

2022-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hyperbilirubinemia. Neonatal jaundice associated with preterm delivery

Interventions

Intervention 1: Intervention group: 5 drop pedilact zist takhmir probiotic .co. Iran daily for 3 days 5 ml/g from first day. And bilirubin level is measured every 24 hours for 7 days. Intervention 2:

Eligibility

Sex/Gender

All

Age

1 Days to 28 Days

Inclusion criteria

Inclusion criteria: Neonate weighting less than 2,500 grams are not in critical condition Do not have krenictrose Do not have ventilation Do not have heart failure Do not have asphyxia and no history of Rh incompatibility Do not have icterus

Exclusion criteria

Exclusion criteria: Critical neonates Phototherapy

Design outcomes

Primary

Measure	Time frame
Bilirubin. Timepoint: Daily for 7 days. Method of measurement: Through the surface of the skin.;Hospitalization period. Timepoint: Daily. Method of measurement: Number of days.	—

Secondary

Measure	Time frame
Weight gain. Timepoint: Daily. Method of measurement: Balance.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNazli Parizadeh

Mashhad University of Medical Sciences

parizadehnazli@gmail.com+98-051-385211121

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026