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Effect of minocycline on COVID-19

Clinical trial of minocycline against COVID-19

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20081019001369N4
Enrollment
40
Registered
2020-04-11
Start date
2020-04-20
Completion date
Unknown
Last updated
2020-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Covid-19. COVID-19 Disease

Interventions

Intervention 1: Intervention group: In addition to the standard treatment regimen forCOVID-19, the minocycline capsule 100 mg will be given two times a day for 2 weeks. Intervention 2: Control group:

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients with covid-19 symptoms Indication of home quarantine and outpatient medication; Age range 18 to 65

Exclusion criteria

Exclusion criteria: Patients connected to a catheter Patients under chemotherapy Patients taking cytotoxic drugs or corticosteroids Pregnant and lactating patients Patients with severe renal insufficiency Patients with liver failure Diabetic patients

Design outcomes

Primary

MeasureTime frame
Time interval until clinical symptoms improve. Timepoint: 3 days, 1 week and 2 weeks after treatment. Method of measurement: time of recovery.

Secondary

MeasureTime frame
Fever. Timepoint: 3 days, 1 week and 2 weeks after treatment. Method of measurement: Thermometer.;Lymphopenia. Timepoint: 3 days, 1 week and 2 weeks after treatment. Method of measurement: Cell counter device.;CRP. Timepoint: 3 days, 1 week and 2 weeks after treatment. Method of measurement: CRP kit.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHossein Hosseinzadeh

Mashhad University of Medical Sciences

hosseinzadehh@mums.ac.ir+98 51 3180 1193

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026