Comparison effect of black seed and Urtica dioica with tamsulosin in the treatment of ureteral stones

Comparison effect of a combined extract of black seed and Urtica dioica with tamsulosin on pain improvement and expulsion of ureteral stones sized 5-10 millimeter in patients older than18 years old

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20081011001323N27

Enrollment

Registered

2021-06-19

Start date

2021-06-01

Completion date

Unknown

Last updated

2021-06-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ureteral stones. Calculus of ureter

Interventions

Intervention 1: Intervention group: combined extract of Black seed and leaf of Urtica dioica (120 mg of Urtica dioica and 120 mg of Black seed) is produced in form of a capsule and is consumed (divide

Eligibility

Sex/Gender

All

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Age more than18 years old Suffering from ureteral stone less than 10 millimeter Having informed consent form

Exclusion criteria

Exclusion criteria: Uncontrolled coagulopathy Azotemia Pregnancy Presence of active urinary tract infection Allergy to medical or herbal drugs Suffering from cardiovascular or pulmonary disease Suffering from hepatic disease Suffering from peptic ulcer disease

Design outcomes

Primary

Measure	Time frame
Passage of ureteral stones with sizes from 5 to 10 millimeters. Timepoint: Two weeks and one month after start of treatment. Method of measurement: Perform KUB and sonography and patient report.	—

Secondary

Measure	Time frame
The severity of pain due to stone passage. Timepoint: During the study , two weeks and one month after starting treatment. Method of measurement: With Visual Analogue Scale (VAS).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSadrolleh Mehrabi

Yasouj University of Medical Sciences

sadrollahm@yahoo.com+98 74 3322 4721

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026