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Review and comparison the success rate, using medroxy progesterone acetate instead of GNRH antagonist,in patients undergoing intracytoplasmic sperm injection (ICSI) by using oocyte donation

Review and comparison the success rate, using medroxy progesterone acetate instead of GNRH antagonis, in patients undergoing intracytoplasmic sperm injection (ICSI) by using oocyte donation, single-blind clinical trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20081007001306N10
Enrollment
216
Registered
2019-07-31
Start date
2019-08-23
Completion date
Unknown
Last updated
2021-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility in female. Female infertility associated with anovulation

Interventions

Intervention 1: Intervention group: prescription two tablets of Medroxyprogesterone containing 5 mg
manufactured by Abouryan company
from the first day of the visit until receiving HCG. Intervention 2: Control group: Receive routine treatment.

Sponsors

Research vice-chancellorship, Guilan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 50 Years

Inclusion criteria

Inclusion criteria: All infertile patients with oocyte donation undergoing ICSI

Exclusion criteria

Exclusion criteria: In the oocyte donor:Age over 35 years, irregular menstruation, antral follicle count less than 5 and more than 12, FSH more than 10 on the third day of menstruation, cystic ovaries and endometriosis, BMI greater than 25, not having at least one child and the presence of any disease affecting ovulation (such as thyroid disease and high prolactin levels) In the oocyte receptor: Age over 50 years , any systemic disease including hypertension, diabetes, chronic diseases, liver and kidney, problem in the uterus and tubes (including: leiomyoma, polyp, adenomyosis, ashren and hydrosalpinx and etc.) and there is male factor

Design outcomes

Primary

MeasureTime frame
Fertility success. Timepoint: Two weeks after fetal transfer. Method of measurement: Pregnancy test.

Secondary

MeasureTime frame
Seeing fetal heart rate. Timepoint: 6 weeks after fetal transfer. Method of measurement: Vaginal ultrasound.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZiba Zahiri

Rasht University of Medical Sciences

drzibazahiri@yahoo.com+98 13 3336 9224

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 7, 2026