Complications of anesthesia during the puerperium. Complications of anesthesia during the puerperium
Conditions
Interventions
Intervention 1: Intervention group: NE norepinephrine group: 45 people: these people receive NE with a dose of 5 micrograms. Intervention 2: Control group: Phenylephrine PE group: 45 people: these peo
Sponsors
Gorgan University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: The participants in this study include pregnant women, 36 to 41 weeks, between 18 and 45 years old, who referred to Sayad Shirazi Hospital in Gorgan. These patients are candidates for elective Cesarean elective Do not have any restrictions for spinal anesthesia such as patient's lack of consent, sensitivity to anesthesia, injection site infection, and high intracerebral pressure. Patients who enter the study in case of failure of spinal anesthesia, unpredictable complications during surgery, such as bleeding during surgery more than normal for a cesarean section without problems (more than 1500 ml) and the sensory level of T4 is higher than are excluded from the study.
Exclusion criteria
Exclusion criteria: At the beginning of the study, patients with uncontrolled heart complications, high blood pressure disorders in pregnancy, diabetes, psychiatric and renal problems, systolic blood pressure less than 90 mm Hg, peripheral bleeding, coagulation disorders
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| In the first few minutes after the injection of both drugs, we expect an increase in blood pressure, and we also expect to maintain the heart rate after the use of norepinephrine. Timepoint: It was monitored every 2 minutes to 6 minutes, every 3 minutes to 15 minutes and every 5 minutes until the end of the surgery. Method of measurement: An increase in blood pressure was calculated as an increase in systolic pressure greater than 120% of baseline and a drop in blood pressure was calculated based on a decrease in systolic blood pressure below 80% of baseline. | — |
Secondary
| Measure | Time frame |
|---|---|
| Due to the short half-life of the drug, which is up to 3 minutes, and its metabolite is also inactive, we do not expect secondary effects. Timepoint: 5 minutes later. Method of measurement: In this study, an increase in blood pressure is calculated as an increase in systolic pressure more than 120% of the baseline, and a drop in blood pressure is calculated based on a decrease in systolic blood pressure below 80% of the baseline. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Erazbardi Ghorchaei
Gorgan University of Medical Sciences
Outcome results
None listed