celiac disease. Celiac disease
Conditions
Interventions
Intervention 1: Intervention group: Including 49 patients, they will use 2 capsules of Lactocar probiotic every day for 6 weeks, with an interval of 12 hours, and along with this medicine, they will f
Sponsors
Gorgan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Confirmation of celiac disease with small intestine biopsy Measurement of antibody titer against tissue transglutaminase (Anti TTg) Age above 18 years
Exclusion criteria
Exclusion criteria: Any recent infections Concomitant inflammatory bowel disease (IBD) Immune deficiency (acquired or non-acquired) Taking drugs that affect the immune system (immune suppressors and stimulants) Recent GI surgery Taking NSAID painkillers or antibiotics in the last 6 weeks Having cancer or being HIV positive Cardiovascular diseases, glands, kidney, liver, neurological or mental malignancy Pregnancy and breastfeeding Alcohol and drug addiction Participation in another similar study within the last 6 months unwillingness to take probiotics patient being out of reach
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The severity and extent of disease symptoms. Timepoint: The beginning of the study and 6 weeks after the start of the study. Method of measurement: CSI ( celiac symptom index ) questionnaire.;Tissue transglutaminase antibody titer (Anti-Ttg). Timepoint: The beginning of the study and 6 weeks after the start of the study. Method of measurement: titer Anti-TTG. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactTaghi Amiriani
Gorgan University of Medical Sciences
Outcome results
None listed