Chronic periodontitis stage I and II. Chronic periodontitis
Conditions
Interventions
Intervention 1: Intervention group: After completing the initial scaling and root planing, a few drops of 0.5 mg / ml Rose Bengal solution and then a few drops of Chitosan nanoparticle solution will b
Sponsors
Tabriz University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Have good general health. At least one tooth with stage1 periodontitis(initial periodontitis) and stage2 periodontitis(moderate periodontitis) that is with a probing depth of =6mm. This tooth is associated with bleeding on probing(BOP) or gingivitis.
Exclusion criteria
Exclusion criteria: Tooth with other symptoms such as mobility, furcation lesions, defect of ridge , and bone destruction or probe depth that leads to the difficulty and complexity of the treatment. Smokers Pregnant women Females on hormone therapy Those who had received systemic or topical antibiotics and/or anti-inflammatory drugs Those who received surgical or non-surgical periodontal treatment within the past 12 months prior to the enrollment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bleeding on probing. Timepoint: 14 and 90 days after completion of scaling and application of Chitosan nanoparticle solution. Method of measurement: Bleeding within 30 seconds after periodontal probe insertion Michigan O Williams marking. | — |
Secondary
| Measure | Time frame |
|---|---|
| Change of probing depth. Timepoint: Baseline, 14 and 90 days after completion of scaling and application of chitosan nanoparticle solution. Method of measurement: periodontal prob of Michigan O With Williams marking.;Clinical attachment level. Timepoint: Baseline, 14 and 90 days after completion of scaling and application of chitosan nanoparticle solution. Method of measurement: periodontal prob of Michigan O With Williams marking.;Gingival recession. Timepoint: Baseline, 14 and 90 days after completion of scaling and application of chitosan nanoparticle solution. Method of measurement: periodontal prob of Michigan O With Williams marking.;Plaque index. Timepoint: Baseline, 14 and 90 days after completion of scaling and application of chitosan nanoparticle solution. Method of measurement: disclosing agents. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactReza Pourabbas
Tabriz University of Medical Sciences
Outcome results
None listed