Radiation-induced xerostomia. Dry mouth, unspecified
Conditions
Interventions
Intervention 1: Intervention group: GaAlAs Low level laser (LLL ) with 810 nm, 200 mw power,3 cm penetration depth using dose 2 j/cm2 ,on 16 points including: 3 points on each parotid gland,2 points
Sponsors
vice chancellor of reasearch of Mashhad University of medical sciences
Eligibility
Sex/Gender
All
Age
20 Years to 75 Years
Inclusion criteria
Inclusion criteria: Age range:20-75 Yrs Suffering from head and neck tumors requiring radiotherapy Involving one of major salivary glands in radiation field Total dose exceeding 20 Gry
Exclusion criteria
Exclusion criteria: Patient or physician dissatisfaction Suffering from minor or major salivary gland tumors Suffering from any systemic disease with potential of xerostomia or consumption of any drug causing xerostomia Presence of xerostomia in initial examination(unstimulated saliva<0.1 ml/min) History of previous radiotherapy Presence of oral mucosal lesions Regration of patient during trial
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Stimulated and unstimulated saliva. Timepoint: before radiotherpay and once weekly during radiotherpay ( mean: 6 weeks) on 8 to 10 a.m. Method of measurement: Unstimulated saliva: during 5 minutes,whole saliva was sputed in glass tube (every 60 minutes , 5 times).saliva was measured in mili liters and grams stimulated saliva: saliva stimulation in 0,30,60,90 and 120 seconds by citric acid 2% soaked swab on lateral borders of tongues. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMahdokht Rashed Mohasel
Mashhad Dentistry School
Outcome results
None listed