Determining the effectiveness of Hyiodine comparison standard treatment on healing of Diabetic Foot Ulcer

Evaluation of the effectiveness of Hyiodine comparison standard treatment on healing of Diabetic Foot Ulcer: a randomized single-blind controlled trial

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20080904001199N8

Enrollment

Registered

2023-08-05

Start date

2023-08-23

Completion date

Unknown

Last updated

2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Diabetic Foot Ulcers. Condition 2: Diabetic Foot Ulcers. Type 1 diabetes mellitus with foot ulcer Type 2 diabetes mellitus with foot ulcer

Interventions

Intervention 1: Control group: These patients will receive standard treatment including washing with normal saline, debridement and dressing. Every week, after performing sharp debridement and washing

Eligibility

Sex/Gender

All

Age

30 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients with diabetic neuropathic and neuroischemic foot ulcers Patients with PEDIS Grade 1 and 2 Diabetic Foot Ulcer Patients with Wagner Grade 1 and 2 Diabetic Foot Ulcer Patient with the hemoglobin A1c less than and equal to 8.5

Exclusion criteria

Exclusion criteria: Getting infected with Covid-19 have skin allergies have thyroid disease have coagulation disorders

Design outcomes

Primary

Measure	Time frame
Wound area. Timepoint: Before the intervention - the first week after the intervention - the second week after the intervention - the third week after the intervention - the fourth week after the intervention. Method of measurement: Using digital calipers and ImageJ software. After washing and debriding the wound to measure the surface of the wound, in addition to photography, a digital caliper is used to calculate the largest length and width of the wound. The depth of the wound is also measured and recorded using a probe.;The bacterial load on the wound surface. Timepoint: Before the intervention - the second week after the intervention- the fourth week after the intervention. Method of measurement: Microbial culture will be done using swap and agar medium. Bacterial colonies are reported qualitatively and quantitatively.	—

Measure

Time frame

Wound area. Timepoint: Before the intervention - the first week after the intervention - the second week after the intervention - the third week after the intervention - the fourth week after the intervention. Method of measurement: Using digital calipers and ImageJ software. After washing and debriding the wound to measure the surface of the wound, in addition to photography, a digital caliper is used to calculate the largest length and width of the wound. The depth of the wound is also measured and recorded using a probe.;The bacterial load on the wound surface. Timepoint: Before the intervention - the second week after the intervention- the fourth week after the intervention. Method of measurement: Microbial culture will be done using swap and agar medium. Bacterial colonies are reported qualitatively and quantitatively.

—

Secondary

Measure	Time frame
Side effects of treatment. Timepoint: throughout the intervention and the fifth week after the intervention. Method of measurement: There will be phone and in-person reviews. Registration is done in the case report form (CRF).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mohammad Reza Amini

Tehran University of Medical Sciences

mramini@tums.ac.ir+98 21 8822 0037

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026