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Comparison of the effect of Agnugol, Cimifugol , Soyagol , vitagnus and EsCitalopram

Comparison of the effect of Agnugol, Cimifugol , Soyagol , vitagnus and EsCitalopram in reducing menopausal symptoms in postmenopausal women

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20080902001181N4
Enrollment
200
Registered
2023-01-21
Start date
2023-01-07
Completion date
Unknown
Last updated
2023-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Menopause. Menopausal and female climacteric states

Interventions

Intervention 1: first intervention group: One CimiFugol coated tablet containing 6.5 mg of dry root of black cohosh plant manufactured by GolDaru Company will be taken daily for 8 weeks every night at

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
45 Years to 65 Years

Inclusion criteria

Inclusion criteria: Obtaining a score of 5 and above from the MRS questionnaire 12 months or more have passed since menopause Age between 45 and 65 years

Exclusion criteria

Exclusion criteria: Presence or history of breast and uterine cancer, abnormal vaginal bleeding, liver, kidney, thyroid, depression and known anxiety disorders. Use of progestins, contraceptive pills, GNRH agonists and antagonists Taking drugs that interact with the studied drugs, such as warfarin, tamoxifen, antipsychotics, and dopamine antagonists.

Design outcomes

Primary

MeasureTime frame
Total score of menopausal symptoms. Timepoint: The total score of menopausal symptoms is checked at the beginning of the study (before the start of the intervention), the fourth and the eighth week after the start of the intervention. Method of measurement: Menopause Rating Scale (MRS).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMansour Siavash

Esfahan University of Medical Sciences

siavash@med.mui.ac.ir+98 31 3668 8138

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026