COVID-19. Covid-19
Conditions
Interventions
Intervention 1: Intervention group: Provita Capsule (each capsule contain vitamin A, E, D, C, B family, Zn, Se, Para-biotic, and inactive ingredients, produced by Tak-Gen-Zist pharmaceutical company,
Sponsors
Bagheiat-allah University of Medical Sciences
Takgen company
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Age: equal or more than 18 years; The patient have written consciously and freely consent to participate in the study; The patient's clinical symptoms (dry cough, shortness of breath, fever) confirm COVID-19. Confirmed diagnosis of COVID-19, with either lung CT-Scan result, which is typical for COVID-19 pulmonary involvement,or RT-PCR confirmation. Less than 7 days have passed since the onset of symptoms.
Exclusion criteria
Exclusion criteria: History of allergy to the ingredients; The patient is in another clinical trial at the same time; The patient needs to receive medical care from the intensive care unit; Pregnancy; Lactation. Impossibility of oral nutrition;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical symptoms (dry cough). Timepoint: Daily monitoring at the hospitalization, but the result of baseline (before the initiation of intervention), and day 7 and day 21 from the initiation, is recorded. Method of measurement: Physical examination,questionnaire.;Clinical symptoms (respiratory distress). Timepoint: Daily monitoring at the hospitalization, but the result of baseline (before the initiation of intervention), and day 7 and day 21 from the initiation, is recorded. Method of measurement: Pulse-oxymetery device.;Clinical symptoms (fever). Timepoint: Daily monitoring at the hospitalization, but the result of baseline (before the initiation of intervention), and day 7 and day 21 from the initiation, is recorded. Method of measurement: Thermometer. | — |
Secondary
| Measure | Time frame |
|---|---|
| Ferritin level. Timepoint: Before the intervention initiation (baseline) and day 90's results will recorded on designed checklist. Method of measurement: Blood sample, laboratory analysis.;Serum level of Interleukin 6. Timepoint: Before the intervention initiation (baseline) and day 90's results will recorded on designed checklist. Method of measurement: Elisa kit.;Serum level of tumor necrosis factor(TNF) alfa. Timepoint: Before the intervention initiation (baseline) and day 90's results will recorded on designed checklist. Method of measurement: Elisa kit.;Serum level of Monocyte chemoattractant protein-1(MCP-1). Timepoint: Before the intervention initiation (baseline) and day 90's results will recorded on designed checklist. Method of measurement: Elisa kit.;Quality of life. Timepoint: Before the intervention initiation (baseline) and day 90's results will recorded on designed checklist. Method of measurement: The 36-Item Short Form Survey (SF-36) questionnaire.;Mood. Timepoint: Before the intervention initiation (baseline) and day 90's results will recorded on designed checklist. Method of measurement: Profile of Mood States(POMS) questionnaire.;Anxiety. Timepoint: Before the intervention initiation (baseline) and day 90's results will recorded on designed checklist. Method of measurement: Perceived Stress Scale (PSS) questionnaire.;C-reactive protein (CRP) level. Timepoint: Before the intervention initiation (baseline) and day 90's results will recorded on designed checklist. Method of measurement: Blood sample, laboratory analysis. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSeyed Hasan Saadat
Bagheiat-allah University of Medical Sciences
Outcome results
None listed