war chemical gas pulmonary disease. Chronic respiratory conditions due to chemicals, gases, fumes and vapors
Conditions
Interventions
Intervention 1: Intervention group: NAC effervescent tablets 600 mg, 3 times a day,and 50 mg of vitamin B6 tablets, PO, daily, for 6 weeks. Intervention 2: Control group: NAC effervescent tablets 60
Sponsors
Vice Chancellor for Research, Baqiyatallah University of Medical Sciences
Eligibility
Sex/Gender
Male
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Chronic lung lesions caused by war chemical gases have been proven; According to the patient's spirometry results, the pulmonary injury is not severe; The patient should have freely informed written consent to participate in the study.
Exclusion criteria
Exclusion criteria: Suffering from lung function-related diseases of lung origin, including asthma, bronchiectasis, etc. Suffering from lung function-related diseases of non-lung origin, including ALS, kyphosis, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Spirometry parameters changes. Timepoint: Before intervention, then 6 weeks later. Method of measurement: Spirometer. | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of life. Timepoint: Before intervention, then 6 weeks later. Method of measurement: ACT Questionnaire.;Total antioxidant capacity. Timepoint: Before intervention, then 6 weeks later. Method of measurement: Total Antioxidant Capacity Assay Kit.;Malondialdehyde (MDA). Timepoint: before intervention, then 6 weeks later. Method of measurement: human Elisa kit.;Superoxide dismutase (SOD). Timepoint: before intervention, then 6 weeks later. Method of measurement: human Elisa kit. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMohammadjavad Ershadi
Bagheiat-allah University of Medical Sciences
Outcome results
None listed