A comparative study of the therapeutic effect of cetirizine and fexofenadine on the control of skin lesions caused by drugs in the intensive care unit(ICU).

Comparative study of the therapeutic effect of citrizine and fexofenadine in the control of medication-induced skin lesions in hospital intensive care unit

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20080901001165N47

Enrollment

Registered

2020-04-16

Start date

2018-12-01

Completion date

Unknown

Last updated

2020-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Drug induced skin eruption. Rash and other nonspecific skin eruption

Interventions

Intervention 1: Intervention group: Fexofenadine tablets 120 mg every 12 hours for 10 days. Intervention 2: Intervention group: Cetirizine 10 mg tablet every 12 hours for 10 days.

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients stay in ICU for at least 48 hours No history of skin diseases Be on medication, so that people in both groups receive their own treatment appropriate to their illness.

Exclusion criteria

Exclusion criteria: The patient is in the ICU for less than 48 hours. Find non-pharmacological skin diseases

Design outcomes

Primary

Measure	Time frame
Type of drug-induced skin lesion. Timepoint: Before intervention, 10 days after intervention. Method of measurement: Questionnaire.;The severity of the skin lesions. Timepoint: Before intervention, 10 days after intervention. Method of measurement: questionnaire.;The extent of skin lesions. Timepoint: Before intervention, 10 days after intervention. Method of measurement: questionnaire.	—

Secondary

Measure	Time frame
Side effect of Faxofenadine. Timepoint: Before intervention, after ten days. Method of measurement: Questionnaire.;Side effect of cetirizine. Timepoint: Before intervention, after ten days. Method of measurement: Questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactYunes panahi

Bagheiat-allah University of Medical Sciences

yunespanahi@sbmu.ac.ir+98 21 8248 2503

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026