gastroesophageal reflux disease. Diseases of oesophagus, stomach and duodenum
Conditions
Interventions
Intervention 1: Intervention group: Aloe Vera capsule for 28 day, twice a day and pantoprazole for 28 day, once a day. Intervention 2: Control group: pantoprazole for 28 day, once a day. Intervention
Sponsors
Tabib daru pharmaceutical company
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Obtaining the informed consent of the patient. Diagnosis of reflux has been confirmed by a physician Considering clinical and para clinical findings. The patient's condition is not life-threatening.
Exclusion criteria
Exclusion criteria: Have been treated with any interactive medication before intervention; such as H2 blocker inhibitors and herbal medicines or drugs that are harmful to treatment for reflux such as theophylline and the like. Participate in another clinical trial at the same time. Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bloat. Timepoint: Before intervention, 2 and 4 weeks after intervention. Method of measurement: Questionnaire.;Nausea and vomiting. Timepoint: Before intervention, 2 and 4 weeks after intervention. Method of measurement: Questionnaire.;Heartburn. Timepoint: Before intervention, 2 and 4 weeks after intervention. Method of measurement: Questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of life. Timepoint: Before intervention, 2 and 4 weeks after intervention. Method of measurement: Heartburn/Reflux Symptoms Questionnaire.;Drug Adverse effects. Timepoint: After prescription of drug. Method of measurement: Data form. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactYunes Panahi
Bagheiat-allah University of Medical Sciences
Outcome results
None listed