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Evaluation of Therapeutic and safety of clemastine fumarate in symptoms and quality of life in secondry Relapsing MS patients

Evaluation of Therapeutic and safety of clemastine fumarate in symptoms and quality of life in secondry Relapsing MS patients

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20080901001165N40
Enrollment
120
Registered
2019-09-06
Start date
2018-08-01
Completion date
Unknown
Last updated
2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple sclerosis. Multiple sclerosis

Interventions

Intervention 1: Intervention group:One milligram pill will take clemastine fumarate every 12 hours for 12 weeks. Intervention 2: Control group:The placebo is taken every 12 hours for 12 weeks.

Sponsors

Bagheiat-allah University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: inclusion criteria : To sign the consent form knowingly. At the same time,not in another clinical study. The patient is between 18-50 years old. only have a secondery recurrent MS.

Exclusion criteria

Exclusion criteria: The patient is pregnant

Design outcomes

Primary

MeasureTime frame
Quality of life. Timepoint: baseline,three months after the start of intervention. Method of measurement: Questionnaire.;Symptoms. Timepoint: baseline, three months after the start of intervention. Method of measurement: Examination and diagnostic procedures.

Secondary

MeasureTime frame
IgG antibody. Timepoint: baseline and three months after the start of intervention. Method of measurement: elisa.;IgE antibody. Timepoint: baseline and three months after the start intervention. Method of measurement: elisa.;Brain and Spinal Cord Plaques. Timepoint: baseline and three months after the start of intervention. Method of measurement: MRI.;IgE antibody. Timepoint: baselines and three months after the start intervention. Method of measurement: elisa.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactTayyebe zamani

Bagheiat-allah University of Medical Sciences

Zamanitayyebe@gmail.com+98 21 2264 0051

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026