The effectiveness of PRP and Erbium laser in the treatment of dark circles around the eyes

Assessing the effectiveness of the combination therapy with Erbium laser and PRP ( Platelet Rich Plasma) in the treatment of periorbital dark circles

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20080901001159N28

Enrollment

Registered

2020-07-20

Start date

2020-06-21

Completion date

Unknown

Last updated

2020-08-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Eye dark circles. -

Interventions

Intervention 1: Control group: (one side of the face) The dark area around the eye is first treated with Erbium laser, and then physiological serum is applied topically on the site for one hour. This

Eligibility

Sex/Gender

All

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: The cause of darkness, structural and reducing fat in this area is not Age between 18 and 50 years old

Exclusion criteria

Exclusion criteria: Active infection in the face Pregnancy and breastfeeding History of cancer

Design outcomes

Primary

Measure	Time frame
Preorbital hyperpigmentation. Timepoint: Session 0, 4 and 6 during treatment and 3 months after treatment. Method of measurement: Intensity of the darkening of the skin around the eyes compared to other areas of the face with Mexameter device.;Satisfaction amount. Timepoint: After completion of treatment. Method of measurement: Comparison of reduction preorbital hyper pigmentation by patient , before and after treatment According to schedule ( score 0 to 10 ).	—

Measure

Time frame

Preorbital hyperpigmentation. Timepoint: Session 0, 4 and 6 during treatment and 3 months after treatment. Method of measurement: Intensity of the darkening of the skin around the eyes compared to other areas of the face with Mexameter device.;Satisfaction amount. Timepoint: After completion of treatment. Method of measurement: Comparison of reduction preorbital hyper pigmentation by patient , before and after treatment According to schedule ( score 0 to 10 ).

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShiva Alavi

Skin and Stem cell Research Center of Tehran University of Medical Sciences

Shiva.alavi@yahoo.com+98 21 2220 1710

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026