Condition 1: Second Stage of Burning. Condition 2: Second Stage of Burning. Condition 3: Second Stage of Burning. Condition 4: Second Stage of Burning. Burn and corrosion of wrist and hand Burn and corrosion of shoulder and upper limb, except wrist and hand Burn and corrosion of hip and lower limb, except ankle and foot Burn and corrosion of ankle and foot
Conditions
Interventions
Intervention 1: Intervention group: Patients with second-degree burns will be used for their hybrid scaffolds based on amenion, silicon nano-fibers and chitosan combined with fibroblast and keratinocy
Sponsors
Skin and Stem Cell Research Center of Tehran Universty of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: Second degree burns Refer at first 24 hours after injury Damage less than 40% Age 18 to 40 years
Exclusion criteria
Exclusion criteria: Chronic kidney disease Other skin lesions chronic liver disease diabetes
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Repair of burned surface. Timepoint: 7, 14, 21,30 and 90 days post-intervention. Method of measurement: masurement of burn surface by ruler.;Wound healing rate. Timepoint: 7, 14, 21,30 and 90 days post-intervention. Method of measurement: photography. | — |
Secondary
| Measure | Time frame |
|---|---|
| Evaluation of tissue repair. Timepoint: 90 day post-intervention. Method of measurement: Biopsy of the burn site. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMohammad Ali Nilfroushzadeh
Skin and Stem Cell Research Center, Tehran University of Medical sciences
Outcome results
None listed