Condition 1: Acute upper respiratory infections of multiple and unspecified sites. Condition 2: Acute bronchiolitis. Condition 3: community acquired pneumonia. Condition 4: community acquired pneumonia. Condition 5: community acquired pneumonia. Acute upper respiratory infections of multiple and unspecified sites Acute bronchiolitis Pneumonia due to Hemophilus influenzae Pneumonia due to Streptococcus pneumoniae Pneumonia, unspecified organism
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients with pulmonary infection aged 20 to 70 years who have the ability to take oral medication. Personal desire to participate in the project and the signing of a written consent
Exclusion criteria
Exclusion criteria: Patients with severe dyspnea, swallowing disorder, or the possibility of aspiration of food and patients who are unable to take medicine orally. Patients with refractory hypoxemia, decreased level of consciousness, hemodynamic instability, hypercapnia, or respiratory fatigue who require hospitalization in special care units. Patients with respiratory failure requiring mechanical ventilation Patients with immunodeficiency, including patients treated with corticosteroids, chemotherapy, malignancies, organ transplants, HIV patients Patients with underlying diseases including cardiovascular disease, uncontrolled blood pressure, uncontrolled diabetes, BMI > 40 pregnant women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Shortness of breath. Timepoint: At beginning and daily every 12 hours up to end of the study. Method of measurement: Modified Medical Research Council (MMRC).;Cough. Timepoint: At beginning and daily every 12 hours up to end of the study. Method of measurement: simplified cough scale.;Blood oxygen saturation. Timepoint: At beginning and daily every 12 hours up to end of the study. Method of measurement: Pulse Oximeter. | — |
Secondary
| Measure | Time frame |
|---|---|
| Fever. Timepoint: At beginning and then every 12 hours up to end of the study. Method of measurement: Termometer.;ALT. Timepoint: At beginning and end of the study. Method of measurement: Intravenous blood test.;Aspartate transaminase. Timepoint: At beginning and end of the study. Method of measurement: Intravenous blood test.;Alkaline phosphatase. Timepoint: At beginning and end of the study. Method of measurement: Intravenous blood test.;Creatinine. Timepoint: At beginning and end of the study. Method of measurement: Intravenous blood test.;BUN. Timepoint: At beginning and end of the study. Method of measurement: Intravenous blood test.;ESR. Timepoint: At beginning and end of the study. Method of measurement: Intravenous blood test.;CBC. Timepoint: At beginning and end of the study. Method of measurement: Intravenous blood test.;C-reactive protein. Timepoint: At beginning and end of the study. Method of measurement: Intravenous blood test.;Alanine transaminase. Timepoint: At beginning and end of the study. Method of measurement: Intravenous blood test.;Mortality rate. Timepoint: During the study. Method of measurement: Number.;Hospitalization. Timepoint: During the study. Method of measurement: Number. | — |
Countries
Iran (Islamic Republic of)
Contacts
Islamic Azad University