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Effects of herbal drug IMFLUNA on patients with COVID-19

Effects of herbal drug IMFLUNA on improving the symptoms of patients with COVID-19: A placebo controled double-blind clinical study

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20080901001157N17
Enrollment
60
Registered
2020-11-29
Start date
2020-11-15
Completion date
Unknown
Last updated
2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COVID-19 pneumonia. Confirmed diagnosis of COVID-19

Interventions

Intervention 1: Intervention group: patients in this group in addition to receiving standard medications, take two 500 mg capsules of the herbal drug three times a day after meals. The herbal capsule

Sponsors

Zarsan Salamat Company
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patients infected with COVID-19 Confirmation of coronavirus infection with chest CT scan and PCR test Age 20 to 70 years Ability to take oral medication Personal desire to participate in the project and the signing of a written consent

Exclusion criteria

Exclusion criteria: Patients with severe dyspnea Patients with reduced level of consciousness or need hospitalization in intensive care units Patients with swallowing disorders or possibility of aspiration of food or unable to take the drug orally Patients with respiratory failure require mechanical ventilation Patients with resistant hypoxemia Patients with organ transplantation; malignant disease; treated with corticosteroids or chemotherapy Patients with uncontrolled blood pressure, uncontrolled diabetes, cardiovascular disease and underlying respiratory disease Pregnant women

Design outcomes

Primary

MeasureTime frame
Blood oxygen saturation. Timepoint: At beginning and regularly during study. Method of measurement: Pulse Oximeter.;Lung inflammation. Timepoint: At beginning and end of the study. Method of measurement: Chest CT scan.;Cough. Timepoint: Night and day during the study. Method of measurement: Questionnaire.;Shortness of breath. Timepoint: Daily during the study. Method of measurement: Questionnaire.

Secondary

MeasureTime frame
Respiratory Rate. Timepoint: At beginning and regularly during study. Method of measurement: Respiratory Count per minute.;C-reactive protein. Timepoint: At beginning and end of the study. Method of measurement: Intravenous blood test.;CBC. Timepoint: At beginning and end of the study. Method of measurement: Intravenous blood test.;ESR. Timepoint: At beginning and end of the study. Method of measurement: Intravenous blood test.;BUN. Timepoint: At beginning and end of the study. Method of measurement: Intravenous blood test.;Creatinine. Timepoint: At beginning and end of the study. Method of measurement: Intravenous blood test.;K. Timepoint: At beginning and end of the study. Method of measurement: Intravenous blood test.;Na. Timepoint: At beginning and end of the study. Method of measurement: Intravenous blood test.;Body temprature. Timepoint: At beginning and daily up to end of the study. Method of measurement: Thermometer.;ALT. Timepoint: At beginning and end of the study. Method of measurement: Intravenous blood test.;AST. Timepoint: At beginning and end of the study. Method of measurement: Intravenous blood test.;ALK. Timepoint: At beginning and end of the study. Method of measurement: Intravenous blood test.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAfsaneh Kafash

Sabzevar University of Medical Sciences

vasei.h@medsab.ac.ir+98 51 4465 1300

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026