Skip to content

The effect of quadriple regimen on the eradication rate of Helicobacter pylori

Comparision of H.pylori eradication rate in quadriple regimen " Bismuth subcytrate , Pantazol,Amoxicillin, Formilid and Probiotic(Lactobacillus reuteri)” with quadriple regimen " Bismuth subcytrate, Pantazol,Amoxicillin, Formilid and placebo.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20080901001155N32
Enrollment
420
Registered
2020-05-31
Start date
2019-12-22
Completion date
Unknown
Last updated
2021-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

En Helicobacter pylori. Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters

Interventions

Intervention 1: Intervention group 1: 14-day quadruple regimen including "Bismuth subcitrate manufactured by Kamidaroo 240 mg 2 times daily, pantazol 40 mg twice daily by Nycomed, amoxicillin made by

Sponsors

Rasht University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Positive Helicobacter pylori in the endoscopy No therapeutic regimen for treatment People over the age of 18 years

Exclusion criteria

Exclusion criteria: Pregnant and breast feeding women Gastric and esophageal malignancy Cirrhosis and Diabetes heart and kidney failure History of seizure, hematologic diseases Immune system deficiency Drug sensitivity including Pentoprazole and Lactobacillus routeri Patients with incomplete treatment With acute gastrointestinal disease (such as acute diarrhea) Chronic gastrointestinal disease (such as inflammatory bowel disease and celiac disease) Kidney failure Nervous disease and those who received antibiotics or acidblocking drugs 6 weeks ago Use of nonsteroidal antiinflammatory drugs (NSAIDs) such as aspirin 3 weeks before treatment or in the past month for any reason

Design outcomes

Primary

MeasureTime frame
Helicobacter pylori eradication. Timepoint: 8 weeks after the end of the treatment. Method of measurement: En Ureas Breath Test with C14.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Fariborz Mansour-Ghanei

Rasht University of Medical Sciences

ghanaie@yahoo.com+98 13 3353 5116

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 12, 2026