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The efficacy of Ursudoxicolic acid combination with fenofibrate in patients with primary sclerosing cholangitis

Comparative study of the effect of the combined method ursodeoxycholic acid and fenofibrate with single-drug method ursodeoxycholic acid on clinical features and Laboratory tests in primary sclerosing cholangitis.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20080901001155N31
Enrollment
30
Registered
2019-05-17
Start date
2019-04-06
Completion date
Unknown
Last updated
2019-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

primary scleroding cholangitis. K80-K87

Interventions

Intervention 1: Intervention group: UDCA drug dose of 300 mg daily 8 to 10 mg per kilogram of body weight divided into two to three doses by So.Se.Pharm plus fenofibrate dose of 200 mg b.i.d for 12 we

Sponsors

Rasht University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patients with PSC disease confirmed by a specialist using ERCP or MRCP.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Primary scleroding cholangitis treatment. Timepoint: Before starting treatment, weeks 6, 12,18,24,30,36 from the point of view ALT, AST, ALP, Gamma- Glutamyl transpeptidase, Bilirubin Total, Bilirubin Direct,Albumin and Prothrombin and weeks 12,24,36 from the point of view TG, Total-Cholesetrol and LDL. Method of measurement: Blood test.

Secondary

MeasureTime frame
Response to treatment and possible side effect. Timepoint: Weeks 6, 12,18,24,30,36 from the point of view ALT, AST, ALP,Gamma-Glutamyl transpeptidase,Bilirubin Total,Bilirubin Direct,Albumin and Protrombin and weeks 12,24,36 from the point of view TG, Total-Cholestrol and LDL. Method of measurement: Blood test.

Countries

Iran (Islamic Republic of)

Contacts

Public Contact???? ?????? ?????

Rasht University of Medical Sciences

farajov@yahoo.com+98 13 3353 5116

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026