Intra-ovarian injection of platelet-rich plasma in patients with poor ovarian response

Evaluation of intra-ovarian injection of platelet-rich plasma in patients with poor ovarian response; a randomized controlled clinical trial

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20080831001141N40

Enrollment

200

Registered

2023-01-17

Start date

2023-02-01

Completion date

Unknown

Last updated

2023-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Decreased ovarian reserve. Female infertility, unspecified

Interventions

Intervention 1: Intervention group: PRP injection will be done on day 8-12 of the menstrual cycle. PRP injection will be performed less than 15 minutes after its preparation by the surgeon and gynecol

Eligibility

Sex/Gender

Female

Age

No minimum to 44 Years

Inclusion criteria

Inclusion criteria: Patients with a history of at least one poor ovarian response Age =44 years BMI <35 kg/m2 FSH <25 IU/L AMH <1.2 ng/ml

Exclusion criteria

Exclusion criteria: Endocrine, autoimmune and hematological disorders Genetic diseases and chromosomal disorders History of cancer Congenital uterine anomalies Endometriosis, severe adenomyosis, hydrosalpinx, fibromatous uterus

Design outcomes

Primary

Measure	Time frame
Increased ovarian reserve: increased number of antral follicles, and increased levels of antimullerin hormone. Timepoint: 6-8 weeks after intraovarian injection of platelet-rich plasma. Method of measurement: Doppler ultrasound and blood test.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMehri Mashayekhy

ROYAN Institute

dr.mashayekhy@yahoo.com+98 21 2356 2647

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026