Poor ovarian response during controlled ovary stimulation in in vitro fertilization cycles. Complications of attempted introduction of fertilized ovum following in vitro fertilization
Conditions
Interventions
Intervention 1: Intervention group: acupuncture is done twice a week during the preceding cycle and the ovarian stimulation is performed by “gonadotropin releasing hormone (GnRH) agonist stopped proto
Sponsors
Royan Institute
Eligibility
Sex/Gender
Female
Age
No minimum to 35 Years
Inclusion criteria
Inclusion criteria: Diagnosis of Poor ovarian response (POR), according to POSSEIDON group criteria (Group 3): Young patients (<35 years) with poor ovarian reserve pre-stimulation parameters (antral follicle count (AFC) <5, anti-Müllerian hormone <1.2 ng/mL).
Exclusion criteria
Exclusion criteria: Premature ovarian failure diagnosis Endometriosis grade III or IV Any contraindications to ovarian stimulation treatment Uterine infertility factor Previous history of ovarian surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total number of retrieved oocytes. Timepoint: 34–36 hours after final oocyte triggering. Method of measurement: The number of oocytes counted by an embryologist.;Total number of MII oocytes. Timepoint: 34–36 hours final oocyte triggering. Method of measurement: The number of metaphase II oocytes counted by an embryologist. | — |
Secondary
| Measure | Time frame |
|---|---|
| Implantation rate. Timepoint: 4-6 weeks after embryo transfer. Method of measurement: By dividing the number of gestational sacs by the number of embryos transferred.;Clinical pregnancy rate. Timepoint: 5-7 weeks after embryo transfer. Method of measurement: By detection of fetal heart beat in vaginal sonography 5 - 7 weeks after transfer. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactArezoo Arabipoor
Royan Institute
Outcome results
None listed