Tinnitus treatment with single or combination medication

Study of Single and Combination Medication Treatment of Tinnitus by Alprazolam and Fluoxetine

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

IRCT

Registry ID

IRCT20080831001138N26

Enrollment

147

Registered

2018-02-17

Start date

2017-12-22

Completion date

Unknown

Last updated

2018-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tinnitus. Tinnitus

Interventions

Intervention 1: Alprazolam: Daily taking of 0.5 mg till the end of the fourth week of treatment. Intervention 2: Oxcarbazepine: In the first week, its initial nightly dose will be 300 mg. After the se

Eligibility

Sex/Gender

All

Age

20 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients with 20-65 years of age Tinnitus history taking at least six months

Exclusion criteria

Exclusion criteria: Acute or chronic middle ear infections History of thyroid and rheumatologic diseases History of occupational exposure to noise Concomitant use of other drugs

Design outcomes

Primary

Measure	Time frame
Tinnitus. Timepoint: Starting Time, Fifth week. Method of measurement: TSI Questionnaire and VAS Score.	—

Secondary

Measure	Time frame
Anxiety. Timepoint: Starting Time(time0), Fifth Week. Method of measurement: Beck Anxiety Inventory (BAI).;Depression. Timepoint: Starting Time(time0), Fifth Week. Method of measurement: Beck Depression Inventory.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Alia Saberi

Rasht University of Medical Sciences

a_saberi@gums.ac.ir+98 13 3322 5242

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026