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Investigating the effect of vaginal washing before Misoprostol insertion on ripening cervix before labor induction

Investigating the effect of vaginal washing before Misoprostol insertion on ripening cervix before labor induction

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20080826001096N7
Enrollment
164
Registered
2019-08-18
Start date
2019-07-23
Completion date
Unknown
Last updated
2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Labor induction. Other failed induction of labour

Interventions

Intervention 1: Intervention group: : Vaginal washing with normal saline 0.9%(20 cc) is performed once before Misoprostol insertion (25 micrograms vaginal in the fornix posterior vaginal ) with a s

Sponsors

Research vice-chancellorship, Guilan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: pregnant women ages 18 to 40 Having 38 to 40 week pregnancy Having singleton pregnancy Having normal fetal heart rate (FHR) Having cephalic presentation Not having a ban on normal vaginal delivery (cephalopelvic disproportion) Having no uterine contractions spontaneously and effectively (less than three contractions in 30 minutes) Having a Bishop score of less than 6 Estimation of fetal weight less than 4000 grams Candidates for termination of pregnancy (post-term pregnancy (42 weeks and more), oligohydramnios, decreased fetal movements, abdominal biophysical profile score, maternal diabetes mellitus, intrauterine growth retardation, and preeclampsia)

Exclusion criteria

Exclusion criteria: Having sensitivity to known prostaglandin (with questions like skin manifestations, hives and rash, dyspnea and coughing, chest pain and blurred vision after taking prostaglandin) Having vaginal bleeding Preterm rupture of membranes Having a history of previous cesarean section or scar on the uterus Having fetal anomaly Having doubts about Chorioamnionitis

Design outcomes

Primary

MeasureTime frame
Success of labor induction. Timepoint: Post-partum. Method of measurement: Duration from induction to active phase of labor.

Secondary

MeasureTime frame
The duration of vaginal Misoprostol to successful labor induction. Timepoint: During labor. Method of measurement: hour.;Vaginal PH. Timepoint: Before and after vaginal washing. Method of measurement: Nitrazine paper.;Duration from induction to end of first stage of labor. Timepoint: During labor until the end of the first stage of labor. Method of measurement: hour.;Duration from induction to active phase of labor. Timepoint: During labor until the active phase of labor. Method of measurement: hour.;Maternal complications (tachysystole, hyperstimulation, etc.). Timepoint: During labor. Method of measurement: Patient complaint.;Neonatal complications include meconium excretion, Apgar score less than 7, admission to the NICU. Timepoint: During labor until after delivery. Method of measurement: Observations by doctor.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZakieh Bakhshipour

Rasht University of Medical Sciences

Zakie.march88@gmail.com+98 131332496

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026