Skip to content

rectal misoprostol on intraoperative blood loss prior to abdominal myomectomy.

Evaluating the effects of rectal misoprostol prior to myomectomy on the volume of hemorrhage in versus of placebo in al Zahra hospital patients with intramural myoma from 2017-2018

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20080826001096N5
Enrollment
94
Registered
2018-04-26
Start date
2018-04-21
Completion date
Unknown
Last updated
2018-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

myoma. Leiomyoma of uterus

Interventions

Intervention 1: Intervention group: 2 pills equal to 400 mcg misoprostol will be placed rectal one hour before the surgery. Intervention 2: Control group: 2 pills vitamin B6 will be placed rectal one

Sponsors

Guilan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: age between 18-50 years 5 or less symptomatic myoma intramoral myoma based on sonography A minimum of 4 cm in size of myoma (because no smaller than 4 cm can produce a lot of bleeding)

Exclusion criteria

Exclusion criteria: anemia (HB less than10) allergy to Misoprostol (By asking questions such as skin sign, hives, rash, shortness of breath, coughing, chest pain after the previous use of Miso Prostol) Cardiopulmonary diseases Hemorrhage disorders obese (Body Mass Index more than35) Uncontrolled blood pressure despite drug use uterine size more than 24 weeks

Design outcomes

Primary

MeasureTime frame
Length of stay in hospital. Timepoint: From admission to exit. Method of measurement: day.

Secondary

MeasureTime frame
Postoperative hemoglobin and hematocrit. Timepoint: 4 and 24 hours after surgery. Method of measurement: blood test.;Blood loss. Timepoint: Intraoperative and postoperative. Method of measurement: On hemoglobin level and Severity of bleeding Total blood volume in the suction bottle + wet gauze and long gauze.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Hosseini

Guilan university of Medical Sciences

f_hoseini@gums.ac.ir+98 13 3336 9224

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026