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Effect of omega 3 fatty acid on bone formation and resorption markers in osteoporotic spinal cord injured patients

Effect of omega 3 fatty acid on bone formation and resorption markers in osteoporotic spinal cord injured patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT138905102709N7
Enrollment
80
Registered
2010-08-28
Start date
2010-08-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Injury of spinal cord, level unspecified. Injury of spinal cord, level unspecified

Interventions

Intervention 1: Injection of two vitamin D ampules (300,000 IU), then one month later, two supplements of Calcium-D capsule (containing 500 mg calcium and 200 IU vitamin D) as well as two capsules of
Treatment - Drugs
Placebo
Injection of two vitamin D ampules (300,000 IU), then one month later, two supplements of Calcium-D capsule (containing 500 mg calcium and 200 IU vitamin D) as well as two capsules of omega 3 (600 mg)
Injection of two vitamin D ampules (300,000 IU), then one month later, two supplements of Calcium-D capsule (containing 500 mg calcium and 200 IU vitamin D) as well as two placebo capsules for four mo

Sponsors

Brain and Spinal Injury Repair Research Center-Endocrine & Metabolism Research Institute
Lead Sponsor
Iran University of Medical Science
Collaborator

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Inclusion criteria: no metabolic, malignant or kidney disorder, BMD: Z score <-2, normal TSH, LH, FSH, prolactin, and testosterone in men and normal prolactin, estradiol, LH, FSH, and TSH in women Exclusion criteria: pregnancy, lactation, presence of bone disease, hypersensitivity to fish or fish oil, hypertension

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
IL-6. Timepoint: before intervention and four months after intervention. Method of measurement: ELIZA.;RANKL. Timepoint: before intervention and four months after intervention. Method of measurement: ELIZA.;Osteoprotegrin. Timepoint: before intervention and four months after intervention. Method of measurement: ELIZA.;B-ALP. Timepoint: before intervention and four months after intervention. Method of measurement: ELIZA.;TNF- a. Timepoint: before intervention and four months after intervention. Method of measurement: ELIZA.—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Hadis Sabour

Brain and Spinal Injury Research Center,

hsabour@farabi.tums.ac.ir+98 21 6658 1560

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026