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Effect of Trazosin on sweating of Sertralin side effect in depressed patients

Effect of Trazosin on sweating of Sertralin side effect in depressed patients: a double blind clinical trial study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT138905064459N1
Enrollment
134
Registered
2010-10-23
Start date
2009-04-04
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depressive Disorder. Depressive episode

Interventions

Intervention 1: control: placebo, tablet 1mg in bed time, for two weeks. Intervention 2: Intervention: Trazosin, Tablet 1m in bed time, for two weeks.
Placebo
Treatment - Drugs
control: placebo, tablet 1mg in bed time, for two weeks
Intervention: Trazosin, Tablet 1m in bed time, for two weeks

Sponsors

Deputy Dean of Research, Hamadan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria: The patients who referred to the psychology clinic of Farshchian Hospital or to the private clinic of the psychologists of Hamadan city and were depressed based on the DSM IV-TR criteria, had sweating side effect due to the consumption of Sertralin Exclusion criteria: not willing to participate in each stage of the experiment, presence of systemic disease such as hypertension, diabetes, presence of other psychological disorder, using other medicine or suffering from the side effect of Trazosin or placebo like orthostatic hypotension, vertigo, headache

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Sweating. Timepoint: Baseline and 2 weeks after the intervention. Method of measurement: visual analog scale.

Secondary

MeasureTime frame
Headache. Timepoint: daily. Method of measurement: case talking.;Sexual insufficiency. Timepoint: daily. Method of measurement: physical axam and case talking.;Orthostatic hypotension. Timepoint: Daily. Method of measurement: physical axam and case talking.;Palpitation. Timepoint: daily. Method of measurement: physical axam and case talking.;Vertigo. Timepoint: Daily. Method of measurement: physical axam and case talking.;Nasal cogestion. Timepoint: Daily. Method of measurement: physical axam and case talking.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Ghaleiha

Deputy Dean of Research, Hamadan University of Medical Sciences

vc_research@umsha.ac.ir, ghaleiha@umsha.ac.ir+98 81 1827 9001

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026