Acute coronary syndrome. Acute Ischaemic Heart Disease
Conditions
Interventions
Intervention 1: Amiodarone, 100mg, IV, in 10 minutes or more before admission to the hospital. Intervention 2: Distilled water as placebo, with the same volume and shape as amiodarone, in 10 minutes o
Treatment - Drugs
Placebo
Distilled water as placebo, with the same volume and shape as amiodarone, in 10 minutes or more, before admission to the hospital
Amiodarone, 100mg, IV, in 10 minutes or more before admission to the hospital
Sponsors
Iranian Emergency and Disaster Managment Center
Iran Univercity of Medical Sciences
Eligibility
Sex/Gender
All
Age
45 Years to 100 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Presence of Acute Coronary Syndrome criteria referred to hospitals with EMS with the following conditions: diffuse precordial or substernal pain with at least 20 min duration and lasts until patient visits by EMS, no other significant diagnosis for present chest pain, age more than 45 years old in men and more than 50 years old in women, Systolic Blood Pressure 100mm/Hg or higher, Pulse Rate equal to 60 or more, no history of drug sensitivity to Amiodarone
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of arrhythmia. Timepoint: on arrival to hospital. Method of measurement: EKG analysis in hospital. | — |
Secondary
| Measure | Time frame |
|---|---|
| Mortality rate. Timepoint: a week and a month later. Method of measurement: Death rate during a month after the internention. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Milad Salimi
Iran University Of Medical Sciences
Outcome results
None listed