Oral flutamide effects on female acne

Comparison of terapeutic effects of Flutamide and Doxicyclin on moderate acne among females

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT138905044310N3

Enrollment

Registered

2010-07-26

Start date

2007-02-14

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acne vulgaris. Acne vulgaris

Interventions

Intervention 1: Flutamide250 mg daily + topical clindamicin 1% for six months. Intervention 2: Doxicyclin 100 mg daily + topical clindamicin 1% for six months.

Treatment - Drugs

Flutamide250 mg daily + topical clindamicin 1% for six months

Doxicyclin 100 mg daily + topical clindamicin 1% for six months

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Inclusion criteria: 1- Female sex 2- Moderate acne 3- Age above 16 4- Having melassma Exclusion criteria 1- Pregnancy and breastfeeding 2- Hepatic disease 3- Taking OCPs or antiandrogenic drugs

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Acne lesion improvment. Timepoint: Every 2 months. Method of measurement: Count of the lesions.	—

Secondary

Measure	Time frame
Side effects of drug. Timepoint: 2 months. Method of measurement: Clinical examination.;Reduction of sebum. Timepoint: 2 months. Method of measurement: Mexameter.;Patient satisfaction. Timepoint: 2 Months. Method of measurement: questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHasan Edalatkhah

Ardebil University of medical sciences

h.edalatkhah@arums.ac.ir+98 45 1225 1401

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026