Irreversible pulpitis. Pulpitis
Conditions
Interventions
Intervention 1: Two dental cartridges of 2% Articaine combined with 20mg of Ketamine. Intervention 2: Two dental cartridges of 2% Articaine combined with 0.2ml normal saline.
Treatment - Drugs
Placebo
Two dental cartridges of 2% Articaine combined with 20mg of Ketamine
Two dental cartridges of 2% Articaine combined with 0.2ml normal saline
Sponsors
Vice Chancellor for Research of Dental School, Isfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Patients aged 18-50 years, in healthy condition (ASA I or ASA II), having a posterior mandibular tooth (premolar or molar tooth) with a vital pulp and diagnosed as irreversible pulpitis, without severe periodontal disease, without any periapical pathological defect as seen in the radiograph of the tooth, without any contraindications for the drugs and substanses used in the study. Exclusion criteria: Patients showing signs of pulp necrosis upon access cavity opening, patients showing any signs or symptoms of allergy or any adverse effects, patients refusing to continue at any stage point.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain. Timepoint: Before and 15 minutes after administration of the local anesthetic. Method of measurement: Visual Analogue Scale (VAS). | — |
Secondary
| Measure | Time frame |
|---|---|
| Pulpal anesthesia. Timepoint: Before and 15 minutes after administration of the local anesthetic. Method of measurement: Pulp tester. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactVahid Sakhaei manesh
Dental School, Isfahan University of Medical Sciences
Outcome results
None listed