The effects of pomegranate juice on type 2 diabetes

The effect of pomegranate juice (no added sugar) consumption on lipid profile, inflammation factor and oxidative stress in overweight or obese patients with type 2 diabetes

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT138904294424N1

Enrollment

Registered

2010-10-18

Start date

2010-05-31

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

diabetes mellitus 2. Non-insulin-dependent diabetes mellitus

Interventions

Intervention 1: intervention Group:pomegranate juice,250 ml/day,8weeks. Intervention 2: Control Group:water,250 ml/day,8 weeks.

Treatment - Drugs

Placebo

intervention Group:pomegranate juice,250 ml/day,8weeks

Control Group:water,250 ml/day,8 weeks

Eligibility

Sex/Gender

All

Age

30 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: male or female, 30 to 50 years old, BMI between 25-35, having type 2 diabetes at least 6 month, taking metformin or glybanclamid, taking atrovastain, simvastatin or levostatin. Exclusion criteria: having the renal or hepatic failure, treatment With HRT, smoking, treatment with insulin, use of multivitamin-mineral 6 months prior to the study.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Fasting Blood Sugar. Timepoint: baseline and after 8 weeks. Method of measurement: spectrophotometry.;Hemoglobin A1c. Timepoint: baseline and after 8weeks. Method of measurement: Chromatography.;Insulin. Timepoint: baseline and after 8 weeks. Method of measurement: ELIZA.;HOMA-IR. Timepoint: Baseline and after 8weeks. Method of measurement: Formula.;Total Cholesterol. Timepoint: Baseline and after8 weeks. Method of measurement: Spectrophotometry.;Triglyceride. Timepoint: Baseline and after8 weeks. Method of measurement: Spectrophotometry.;HDL. Timepoint: Baseline and after 8 weeks. Method of measurement: Spectrophotometry.;LDL. Timepoint: Baseline and after 8weeks. Method of measurement: Friedewald Formula.;Malondialdehyde. Timepoint: Baseline and after 8 weeks. Method of measurement: Spectrophotometry.;Glutathione peroxidase. Timepoint: Baseline and after 8 weeks. Method of measurement: Spectrophotometry.;Superoxide dismutase. Timepoint: Baseline and after 8 weeks. Method of measurement: Spectrophotometry.;Total Antioxidant Capacity (TAC). Timepoint: Baseline and after 8 weeks. Method of measurement: Spectrophotometry.;HsCRP. Timepoint: baseline and after 8 weeks. Method of measurement: immunotorbidometry.	—

Measure

Time frame

Fasting Blood Sugar. Timepoint: baseline and after 8 weeks. Method of measurement: spectrophotometry.;Hemoglobin A1c. Timepoint: baseline and after 8weeks. Method of measurement: Chromatography.;Insulin. Timepoint: baseline and after 8 weeks. Method of measurement: ELIZA.;HOMA-IR. Timepoint: Baseline and after 8weeks. Method of measurement: Formula.;Total Cholesterol. Timepoint: Baseline and after8 weeks. Method of measurement: Spectrophotometry.;Triglyceride. Timepoint: Baseline and after8 weeks. Method of measurement: Spectrophotometry.;HDL. Timepoint: Baseline and after 8 weeks. Method of measurement: Spectrophotometry.;LDL. Timepoint: Baseline and after 8weeks. Method of measurement: Friedewald Formula.;Malondialdehyde. Timepoint: Baseline and after 8 weeks. Method of measurement: Spectrophotometry.;Glutathione peroxidase. Timepoint: Baseline and after 8 weeks. Method of measurement: Spectrophotometry.;Superoxide dismutase. Timepoint: Baseline and after 8 weeks. Method of measurement: Spectrophotometry.;Total Antioxidant Capacity (TAC). Timepoint: Baseline and after 8 weeks. Method of measurement: Spectrophotometry.;HsCRP. Timepoint: baseline and after 8 weeks. Method of measurement: immunotorbidometry.

—

Secondary

Measure	Time frame
Dietary Factors. Timepoint: Baseline and after 8 weeks. Method of measurement: 3-day food record.;Body Mass Index. Timepoint: Baseline and after 8 weeks. Method of measurement: Formula.;Blood Pressure. Timepoint: Baseline and after 8 weeks. Method of measurement: Sphygmomanometer.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Ebrahimi

Faculty of Health and Nutrition, Tabriz University of Medical Sciences

ebrahimimamagani@tbzmed.ac.ir , samira_b_amini@yahoo.com+98 41 1335 7580

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026